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It should be noted however, even low intensity exercise if prolonged enough in duration can result in significant elevations in testosterone (Galbo et al. Previous research has established that under certain circumstances a negative relationship exists between the hormones cortisol and testosterone. Bambino and Hsueh (1981) showed a direct inhibitory effect of high doses of glucocorticoids upon testicular Leydig cell function in rats, which resulted in a decrease in the production of testosterone. These latter researchers speculated cortisol disrupted the testicular testosterone production process (i. While this previous research has identified this inverse, negative relationship between cortisol and testosterone, studies thus far have apparently not statistically examined this point closely or have done so with inadequate sample sizes. Also, while pharmacological doses of cortisol appear to have a strong effect on circulating testosterone concentrations in humans, the strength of the in vivo relationship at rest and in recovery from exercise has not been thoroughly determined. This last point is important as many published exercise physiology studies have inferred that observed testosterone reductions following certain forms of physical exercise are caused by cortisol elevations in response to the exercise.

 

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